Techno-economic analysis (TEA) is an integral component of research in the Laboratory for Strategic Materials, providing a quantitative framework to evaluate the technical feasibility, economic viability, and scalability of critical materials extraction and recycling technologies. We apply TEA to assess processes developed within the group—including hydrometallurgy, supercritical fluid extraction, electrodialysis, and integrated recycling flowsheets—across a range of primary resources, industrial wastes, and electronic wastes. By linking process performance, material recovery, energy and reagent consumption, and cost drivers, our TEA studies help identify key bottlenecks, guide process optimization, and support the translation of laboratory-scale innovations toward industrial implementation and sustainable materials supply chains.